Opportunity Information: Apply for PAR 18 265
The Institutional Development Award (IDeA) Program Infrastructure for Clinical and Translational Research (IDeA-CTR) opportunity (PAR 18-265) is a National Institutes of Health (NIH) funding announcement designed to build and strengthen the practical, statewide capacity needed to carry out clinical and translational research in IDeA-eligible states. Rather than primarily paying for a single research project, this program focuses on creating shared infrastructure and resources that investigators across participating institutions can use to develop, launch, and compete more effectively for future clinical and translational research funding. The award mechanism is a U54 cooperative agreement, which generally means recipients should expect substantial involvement and collaboration with NIH program staff during planning, implementation, and oversight, and the opportunity is listed as "Clinical Trial Optional," allowing (but not requiring) clinical trial activities depending on what the center proposes.
A central expectation of an IDeA-CTR Center is that it provides added value beyond what typical, individual research grants can reasonably support. In practice, that means building capabilities that are hard to assemble piecemeal through standard R-series awards, such as shared cores, training and mentoring structures, research coordination services, regulatory support, community engagement capacity, biostatistics and informatics resources, and other enabling functions that make clinical and translational studies more feasible and higher quality. The intended outcome is a stronger pipeline of investigators and projects that can successfully attract additional external funding and elevate the overall competitiveness of the state or region in biomedical research that translates discoveries into improvements in patient care and public health.
Applicants are required to establish a statewide network that connects collaborating and partnering institutions and organizations. While the program is anchored in a statewide model, it also allows inclusion of partners outside the state when doing so meaningfully expands the reach or effectiveness of the network. A key constraint is that only one award will be made per IDeA-eligible state, and accordingly, only one application should be submitted per state. This pushes institutions within a state to coordinate, align priorities, and submit a unified proposal that represents the statewide approach rather than multiple competing applications.
Eligibility includes a broad set of domestic organizations involved in higher education and research, including public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both those with 501(c)(3) status and those without). The announcement also highlights that certain institution types may be eligible as "other eligible applicants," including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). Foreign participation is explicitly restricted: non-U.S. entities are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed under this program.
From an administrative standpoint, the opportunity is categorized as discretionary funding and uses the cooperative agreement instrument. The funding activity category is health, and the CFDA listing is 93.859. The source data lists an award ceiling of $4,000,000, indicating the upper bound referenced for funding under this announcement. The original closing date shown is 2019-10-02, and the announcement record reflects a creation date of 2017-11-30. Overall, the program is best understood as an NIH investment in shared clinical and translational research capacity: building a coordinated statewide network and the supporting infrastructure that makes it easier for investigators to initiate strong studies, improve research quality and efficiency, and compete for larger, project-focused funding in the future.Apply for PAR 18 265
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Institutional Development Award (IDeA) Program Infrastructure for Clinical and Translational Research (IDeA-CTR)(U54 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859.
- This funding opportunity was created on 2017-11-30.
- Applicants must submit their applications by 2019-10-02. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $4,000,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
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FAQs: IDeA Program Infrastructure for Clinical and Translational Research (IDeA-CTR) (PAR 18-265)
What is the IDeA-CTR opportunity (PAR 18-265)?
The Institutional Development Award (IDeA) Program Infrastructure for Clinical and Translational Research (IDeA-CTR) opportunity (PAR 18-265) is a National Institutes of Health (NIH) funding announcement intended to build and strengthen the practical, statewide capacity needed to conduct clinical and translational research in IDeA-eligible states.
What is the main purpose of this program?
The program focuses on creating shared infrastructure and resources that investigators across participating institutions can use to develop, launch, and compete more effectively for future clinical and translational research funding, improving the state's or region's overall competitiveness in translating discoveries into improvements in patient care and public health.
Is this grant meant to fund a single research project?
No. Rather than primarily paying for a single research project, the IDeA-CTR program emphasizes building shared capabilities (infrastructure and resources) that support multiple investigators and projects across a statewide network.
What does it mean that the award mechanism is a U54 cooperative agreement?
A U54 cooperative agreement generally means recipients should expect substantial involvement and collaboration with NIH program staff during planning, implementation, and oversight, compared with typical grant mechanisms with less direct programmatic involvement.
Are clinical trials required under this opportunity?
No. The opportunity is listed as "Clinical Trial Optional," meaning clinical trial activities are allowed but not required, depending on what the proposed center includes.
What kinds of activities or infrastructure is an IDeA-CTR Center expected to build?
The announcement emphasizes added value beyond what individual research grants typically support. Examples of shared capabilities described include shared cores, training and mentoring structures, research coordination services, regulatory support, community engagement capacity, biostatistics resources, informatics resources, and other enabling functions that make clinical and translational studies more feasible and higher quality.
What does "added value beyond typical individual research grants" mean in this context?
It means the center should develop capabilities that are difficult to assemble piecemeal through standard R-series awards, by creating shared statewide resources and services that multiple investigators can access to improve research feasibility, quality, and efficiency.
What is the expected outcome of establishing an IDeA-CTR Center?
The intended outcome is a stronger pipeline of investigators and projects that can successfully attract additional external funding and elevate the overall competitiveness of the state or region in clinical and translational biomedical research.
Is a statewide network required?
Yes. Applicants are required to establish a statewide network that connects collaborating and partnering institutions and organizations.
Can the network include partners outside the state?
Yes. While the model is statewide, the program allows inclusion of partners outside the state when that meaningfully expands the reach or effectiveness of the network.
How many awards can be made per IDeA-eligible state?
Only one award will be made per IDeA-eligible state.
Does that mean multiple institutions in a state can each submit an application?
No. Because only one award will be made per state, only one application should be submitted per state. This encourages institutions within a state to coordinate and submit a unified statewide proposal rather than competing applications.
Who is eligible to apply?
Eligibility includes a broad set of domestic organizations involved in higher education and research, including public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (including those with 501(c)(3) status and those without).
Are any specific institution types highlighted as eligible?
Yes. The announcement highlights that certain institution types may be eligible as "other eligible applicants," including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are foreign organizations eligible to apply?
No. Non-U.S. entities are not eligible to apply under this program.
Can a U.S. organization include a non-domestic component in the application?
No. Non-domestic components of U.S. organizations are not eligible.
Are foreign components allowed in any form?
No. Foreign components (as defined by the NIH Grants Policy Statement) are not allowed under this program.
What type of funding is this categorized as?
The opportunity is categorized as discretionary funding and uses the cooperative agreement instrument.
What is the funding activity category?
The funding activity category is health.
What CFDA number is associated with this opportunity?
The CFDA listing provided is 93.859.
What is the award ceiling for this opportunity?
The source data lists an award ceiling of $4,000,000, indicating the upper bound referenced for funding under this announcement.
What was the closing date shown for this announcement?
The original closing date shown is 2019-10-02.
When was the announcement record created?
The announcement record reflects a creation date of 2017-11-30.
In plain terms, what is NIH investing in through IDeA-CTR?
NIH is investing in shared clinical and translational research capacity: a coordinated statewide network plus supporting infrastructure that helps investigators initiate stronger studies, improve research quality and efficiency, and become more competitive for larger, project-focused funding in the future.
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| Centers of Biomedical Research Excellence (COBRE) (P20 Clinical Trial Optional) Apply for PAR 18 266 Funding Number: PAR 18 266 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Youth Violence Prevention Interventions that Incorporate Racism/Discrimination Prevention (R01-Clinical Trial Required) Apply for RFA MD 18 005 Funding Number: RFA MD 18 005 Agency: National Institutes of Health Category: Health Funding Amount: $500,000 |
| NIBIB Research Project Grant (R01 Clinical Trial Required) Apply for PA 18 418 Funding Number: PA 18 418 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIH-CASIS Coordinated Microphysiological Systems Program for Translational Research in Space (UG3/UH3) (Clinical Trials Not Allowed) Apply for RFA TR 18 001 Funding Number: RFA TR 18 001 Agency: National Institutes of Health Category: Health Funding Amount: $500,000 |
| Research on Pre-Exposure Prophylaxis (PrEP) to Prevent HIV in Health Disparity Populations (R01-Clinical Trial Not Allowed) Apply for RFA MD 18 003 Funding Number: RFA MD 18 003 Agency: National Institutes of Health Category: Health Funding Amount: $350,000 |
| NHLBI Clinical Trial Pilot Studies (R34 - Clinical Trial Optional) Apply for PAR 18 463 Funding Number: PAR 18 463 Agency: National Institutes of Health Category: Health Funding Amount: $225,000 |
| Cooperative Centers on Human Immunology (U19 Clinical Trial Optional) Apply for RFA AI 17 040 Funding Number: RFA AI 17 040 Agency: National Institutes of Health Category: Health Funding Amount: $2,400,000 |
| Understanding Immunopathogenesis of Tuberculosis in HIV-1 Infected and Exposed Children (R01 Clinical Trial Not Allowed) Apply for RFA AI 17 039 Funding Number: RFA AI 17 039 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NINDS Advanced Postdoctoral Career Transition Award to Promote Diversity in Neuroscience Research (K22) - Clinical Trial Not Allowed Apply for PAR 18 469 Funding Number: PAR 18 469 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NINDS Advanced Postdoctoral Career Transition Award to Promote Diversity in Neuroscience Research (K22) - Clinical Trial Required Apply for PAR 18 468 Funding Number: PAR 18 468 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Initiation of a Mental Health Family Navigator Model to Promote Early Access, Engagement and Coordination of Needed Mental Health Services for Children and Adolescents (R01- Clincal Trial Required) Apply for PAR 18 428 Funding Number: PAR 18 428 Agency: National Institutes of Health Category: Health Funding Amount: $500,000 |
| Clinical and Translational Science Award U54 (Clinical Trial Optional) Apply for PAR 18 464 Funding Number: PAR 18 464 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Pilot Effectiveness Trials for Post-Acute Interventions and Serivces to Optimize Longer-Term Outcomes (R34-Clinical Trials Required) Apply for PAR 18 431 Funding Number: PAR 18 431 Agency: National Institutes of Health Category: Health Funding Amount: $225,000 |
| NINDS Faculty Development Award to Promote Diversity in Neuroscience Research (K01) - Clinical Trial Not Allowed Apply for PAR 18 490 Funding Number: PAR 18 490 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NINDS Faculty Development Award to Promote Diversity in Neuroscience Research (K01) - Clinical Trial Required Apply for PAR 18 486 Funding Number: PAR 18 486 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Prevention and Treatment Research to Address HIV/AIDS Disparities in Women in the US (R01-Accepting applications that either propose or do not propose clinical trial(s)) Apply for RFA MD 18 004 Funding Number: RFA MD 18 004 Agency: National Institutes of Health Category: Health Funding Amount: $350,000 |
| NIBIB Supplements to NCATS CTSA Programs for Translational Research Teams of Quantitative Researchers and Clinician-Scientists (Admin Supp) Apply for PA 18 426 Funding Number: PA 18 426 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| First in Human and Early Stage Clinical Trials of Novel Investigational Drugs or Devices for Psychiatric Disorders (U01-Clinical Trial Required) Apply for PAR 18 427 Funding Number: PAR 18 427 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Effectiveness Trials for Post-Acute Interventions and Services and Services to Optimize Longer-Term Outcomes (R01-Clinical Trials Required) Apply for PAR 18 430 Funding Number: PAR 18 430 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NEI Audacious Goals Initiative: Translation-Enabling Models to Evaluate Survival and Integration of Regenerated Neurons in the Visual System (U24 Clinical Trials Not Allowed) Apply for RFA EY 17 003 Funding Number: RFA EY 17 003 Agency: National Institutes of Health Category: Health Funding Amount: $1,000,000 |
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