Opportunity Information: Apply for HRSA 26 110
The HIV Technical Assistance for Indian Country opportunity (HRSA-26-110) is a 4-year cooperative agreement program run by the Health Resources and Services Administration (HRSA), HIV/AIDS Bureau, using funds from the U.S. Department of Health and Human Services Minority HIV/AIDS Fund (MHAF). It was designed with input from the Indian Health Service (IHS), specifically the Division of Clinical and Community Services, HIV/HCV/STI Branch, which will consult with awardees during implementation. The overall aim is to strengthen HIV prevention, testing, and treatment systems in tribal and urban Indian settings by building organizational and workforce capacity and by making sustainable, system-level improvements rather than one-time trainings. The program is focused on three core HIV outcomes in Indian Country: improving identification of people who have HIV but are not yet diagnosed, increasing linkage to care and re-engagement for people who have fallen out of care, and improving viral suppression for people receiving HIV treatment.
HRSA expects to fund three entities, each operating within a defined service area, to act as technical assistance providers and capacity builders for tribal and urban Indian organizations. Awardees are expected to take a practical, implementation-oriented approach that helps clinics and programs change workflows, strengthen protocols, and improve performance across the HIV care continuum. In other words, the funded entities are not simply expected to deliver general education; they are expected to help organizations put improved systems into place, support staff in using those systems, and show that the assistance is leading to measurable changes in practice.
The work begins with a structured review of what already exists. Each funded entity must examine prior landscape analyses and previously developed training and technical assistance (T/TA) resources related to strengthening HIV prevention, testing, and treatment in tribal and urban Indian health organizations. The point of this step is to avoid reinventing the wheel while clearly identifying gaps in available T/TA, especially gaps that are specific to the realities of tribal health systems, urban Indian health programs, and their staffing, data, confidentiality, and referral environments. Building from that review, awardees must then create a T/TA plan that lays out how they will conduct individualized needs assessments with participating organizations, what goals and learning objectives they will pursue, what types of materials and supports they will provide (for example, tools, templates, coaching, trainings, and workflow resources), and how they will structure at least one learning collaborative, including its topic, learning objectives, and likely participant roles.
A central requirement is tailoring. Awardees must adapt materials and deliver T/TA at two levels: the provider/staff level (supporting clinicians, nurses, outreach workers, case managers, testers, pharmacists, data staff, and program leaders in their day-to-day roles) and the system level (helping the organization strengthen policies, procedures, workflows, partnerships, and data and quality processes). The expectation is that assistance will be customized to each tribal or urban Indian organization’s needs and readiness, recognizing that organizations may differ widely in resources, service scope, patient population, geography, and current HIV infrastructure. This emphasis on tailored support is meant to make the improvements stick and to ensure they fit the operational context of each site.
Another major deliverable is the development and implementation of a learning collaborative for tribal and/or urban Indian organization staff. The collaborative model is intended to speed up peer learning and collective impact by bringing organizations together to share what works, troubleshoot common barriers, and standardize effective practices where appropriate. The collaborative is expected to have defined topics and learning objectives and to engage relevant participants across disciplines, supporting shared problem-solving around improving testing and identification, strengthening linkage and re-engagement, and increasing viral suppression. This peer-based structure is designed to reduce isolation among programs, spread effective approaches faster, and create a community of practice that can continue beyond the period of intensive support.
Finally, awardees must evaluate the effectiveness of the T/TA they provide. This includes assessing whether organizations are actually implementing the methodologies, tools, and techniques introduced through assistance, and whether that implementation is translating into improved system performance connected to the program’s aims. While the notice emphasizes implementation of what is learned, the broader intent is continuous improvement: using evaluation findings to refine technical assistance, strengthen adoption, and demonstrate that the approach is helping tribal and urban Indian organizations make sustainable changes that support better HIV outcomes.
From an administrative standpoint, this is a discretionary funding opportunity under the Health activity category (CFDA 93.899), offered as a cooperative agreement, which typically means substantial federal involvement in program oversight and coordination compared to a standard grant. The application deadline is July 10, 2026. The award ceiling is $1,500,000, and HRSA anticipates making three awards. Eligible applicants are broad and include tribal governments and tribal organizations, urban- and community-serving nonprofits (with or without 501(c)(3) status), state and local governments, public and private institutions of higher education, school districts, and special district governments, reflecting the program’s intent to fund capable regional or national technical assistance providers that can effectively serve tribal and urban Indian organizations within their service areas.Apply for HRSA 26 110
- The Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "HIV Technical Assistance for Indian Country" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.899.
- This funding opportunity was created on 2026-06-08.
- Applicants must submit their applications by 2026-07-10. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education.
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HIV Technical Assistance for Indian Country (HRSA-26-110) FAQs
What is the HIV Technical Assistance for Indian Country opportunity (HRSA-26-110)?
HRSA-26-110 is a 4-year cooperative agreement program administered by the Health Resources and Services Administration (HRSA), HIV/AIDS Bureau. It uses funding from the U.S. Department of Health and Human Services Minority HIV/AIDS Fund (MHAF) to support technical assistance and capacity-building for tribal and urban Indian settings.
What is the overall purpose of this program?
The program aims to strengthen HIV prevention, testing, and treatment systems in tribal and urban Indian settings by building organizational and workforce capacity and making sustainable, system-level improvements (not just one-time trainings).
Which federal offices are involved in designing and implementing the program?
HRSA designed the opportunity with input from the Indian Health Service (IHS), specifically the Division of Clinical and Community Services, HIV/HCV/STI Branch. During implementation, IHS will consult with awardees.
What are the core HIV outcomes this program is focused on in Indian Country?
The program focuses on three outcomes across the HIV care continuum: (1) improving identification of people who have HIV but are not yet diagnosed, (2) increasing linkage to care and re-engagement for people who have fallen out of care, and (3) improving viral suppression for people receiving HIV treatment.
How many awards does HRSA expect to make?
HRSA anticipates making three awards.
What is the award ceiling?
The award ceiling is $1,500,000.
How long is the project period?
The project period is 4 years.
What type of funding mechanism is this?
This is a cooperative agreement, which typically involves substantial federal involvement in program oversight and coordination compared with a standard grant.
What is the CFDA number and activity category?
The opportunity is under the Health activity category with CFDA 93.899.
When is the application deadline?
The application deadline is July 10, 2026.
Who is eligible to apply?
Eligible applicants include tribal governments and tribal organizations; urban- and community-serving nonprofits (with or without 501(c)(3) status); state and local governments; public and private institutions of higher education; school districts; and special district governments.
Is 501(c)(3) status required for nonprofit applicants?
No. The eligibility description includes urban- and community-serving nonprofits with or without 501(c)(3) status.
Who are the intended beneficiaries of the technical assistance?
The technical assistance is intended for tribal and urban Indian organizations, with the goal of strengthening their HIV prevention, testing, and treatment systems.
What is HRSA expecting awardees to do, at a high level?
HRSA expects awardees to serve as technical assistance providers and capacity builders in a defined service area, helping tribal and urban Indian organizations implement practical, workflow- and system-focused improvements that lead to measurable changes in practice across the HIV care continuum.
Does the program focus on general education and one-time trainings?
No. The emphasis is on sustainable, system-level improvements rather than one-time trainings. Education may be part of the approach, but the expectation is implementation support that results in changed workflows, stronger protocols, and improved performance.
What does “implementation-oriented” technical assistance mean in this program?
It means the funded entities are expected to help clinics and programs change workflows, strengthen protocols, and improve performance, support staff in using improved systems, and demonstrate that the assistance is leading to measurable changes in practice.
Will awardees work within a specific service area?
Yes. HRSA expects to fund three entities, each operating within a defined service area, to provide technical assistance and capacity building.
What is the first major step awardees must take once funded?
Each funded entity must conduct a structured review of what already exists by examining prior landscape analyses and previously developed training and technical assistance (T/TA) resources related to strengthening HIV prevention, testing, and treatment in tribal and urban Indian health organizations.
Why does the program require reviewing prior analyses and existing T/TA resources?
The purpose is to avoid reinventing the wheel while identifying gaps in available T/TA, especially gaps specific to tribal health systems and urban Indian health programs, including issues related to staffing, data, confidentiality, and referral environments.
What is a T/TA plan in the context of this opportunity?
A T/TA plan is the awardee’s plan describing how individualized needs assessments will be conducted with participating organizations, the goals and learning objectives to be pursued, the types of materials and supports to be provided (such as tools, templates, coaching, trainings, and workflow resources), and how at least one learning collaborative will be structured.
Are individualized needs assessments required?
Yes. Awardees are expected to conduct individualized needs assessments with participating organizations as part of developing and delivering tailored technical assistance.
What kinds of technical assistance supports are mentioned in the notice?
Examples include tools, templates, coaching, trainings, and workflow resources. The intent is to provide practical supports that help organizations implement improved systems and practices.
What does “tailoring” mean for this program?
Tailoring means adapting materials and delivering technical assistance at two levels: (1) the provider/staff level (supporting day-to-day roles across clinical and program functions) and (2) the system level (strengthening organizational policies, procedures, workflows, partnerships, and data and quality processes). Support is expected to be customized to each organization’s needs and readiness.
Which staff roles are specifically mentioned as being supported through T/TA?
The notice mentions supporting clinicians, nurses, outreach workers, case managers, testers, pharmacists, data staff, and program leaders.
What kinds of system-level improvements are within scope?
The opportunity highlights system-level work such as strengthening policies, procedures, workflows, partnerships, and data and quality processes to improve performance across HIV prevention, testing, linkage/re-engagement, and treatment outcomes.
Why does the program emphasize customization to each site?
The notice notes that tribal and urban Indian organizations can differ widely in resources, service scope, patient population, geography, and current HIV infrastructure. Customization is intended to make improvements stick and fit each site’s operational context.
Is a learning collaborative required?
Yes. Awardees must develop and implement at least one learning collaborative for tribal and/or urban Indian organization staff.
What is the intended purpose of the learning collaborative?
The collaborative model is intended to accelerate peer learning and collective impact by bringing organizations together to share what works, troubleshoot common barriers, and standardize effective practices where appropriate, especially around testing/identification, linkage and re-engagement, and viral suppression.
What must be defined for the learning collaborative?
The learning collaborative is expected to have defined topics and learning objectives and to engage relevant participants across disciplines.
What is meant by creating a “community of practice”?
The notice describes the collaborative as a peer-based structure designed to reduce isolation among programs, spread effective approaches faster, and create a community of practice that can continue beyond the period of intensive support.
How will awardees be expected to evaluate their technical assistance?
Awardees must evaluate effectiveness by assessing whether organizations are implementing the methodologies, tools, and techniques introduced through T/TA, and whether that implementation translates into improved system performance connected to the program’s aims.
Is the evaluation focused only on satisfaction with trainings?
No. The notice emphasizes implementation of what is learned and continuous improvement, using evaluation findings to refine technical assistance, strengthen adoption, and demonstrate sustainable changes that support better HIV outcomes.
What does HRSA mean by “measurable changes in practice”?
Within the description provided, it refers to showing that technical assistance leads to organizations putting improved systems into place, staff using those systems, and resulting improvements in system performance related to identification/diagnosis, linkage and re-engagement, and viral suppression.
Is this opportunity meant to support direct clinical services?
The description provided focuses on technical assistance and capacity building to strengthen systems (workflows, protocols, data and quality processes, and staff capability) rather than describing direct service delivery funding.
What makes this opportunity different from a typical training grant?
It is framed around sustainable, system-level improvements and hands-on implementation support, including individualized needs assessments, tailored supports at staff and system levels, participation in a learning collaborative, and evaluation of whether changes are adopted and improving performance.
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