Opportunity Information: Apply for RFA AA 20 002
The Comprehensive Alcohol Research Centers (P60 Clinical Trial Optional) funding opportunity (RFA-AA-20-002) is a National Institutes of Health grant run through the National Institute on Alcohol Abuse and Alcoholism (NIAAA). It is designed to support large, interdisciplinary alcohol research centers that bring together multiple investigators and complementary lines of work to address alcohol use disorder (AUD) and the broader impacts of alcohol on health and disease. The basic idea is to fund coordinated, collaborative research programs that can do more than isolated projects by creating a shared scientific vision, common resources, and cross-cutting methods that move the field forward.
NIAAA is looking for centers that provide leadership in alcohol-related research, including development of research methods and broad dissemination of findings and tools. The scientific scope is intentionally broad and can include studies on the nature and causes of AUD, including etiology and genetics, as well as improvements in diagnosis, treatment, and prevention. The opportunity also emphasizes research on alcohol-related end-organ diseases and other health consequences, and it recognizes that alcohol can have biomedical, psychosocial, and economic impacts across the entire lifespan. Where it is relevant and a significant public health concern, research on comorbid conditions can be included, reflecting the reality that AUD often overlaps with other disorders and health challenges.
A major expectation of the center model is innovation and infrastructure. Beyond producing findings, funded centers are meant to be drivers of new research methods, technologies, and approaches that enable sustained, goal-directed work. In practice, this typically means building shared cores, harmonized protocols, and collaborative structures that help multiple projects work together efficiently and produce results that are larger in impact than the sum of individual studies. The notice also indicates that clinical trials are optional, meaning applicants may propose clinical trial work if it fits their aims, but they are not required to include a clinical trial to be competitive.
Eligibility is broad and includes many types of U.S.-based organizations. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other Native American tribal organizations; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories as listed); for-profit organizations (other than small businesses); and small businesses. The opportunity also explicitly highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, tribal governments that are not federally recognized, and U.S. territories or possessions.
Foreign eligibility is restricted in a specific way. Non-domestic (non-U.S.) entities and non-domestic (non-U.S.) institutions are not eligible to apply as the primary applicant organization, and non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components are allowed when they meet the NIH definition in the NIH Grants Policy Statement, meaning a U.S. applicant may include certain foreign collaborations or activities as part of the overall project when well-justified and consistent with NIH policy.
From the source details provided, this is a discretionary grant in the health category (CFDA 93.273). The opportunity lists an award ceiling of $1,250,000, with an original closing date of 2019-11-14, and a creation date of 2019-07-11. Overall, the program is structured to support high-impact, collaborative center-based research that advances understanding of AUD and alcohol-related harms, while also building durable scientific capabilities and sharing knowledge and tools that can influence the field beyond the funded institution.Apply for RFA AA 20 002
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Comprehensive Alcohol Research Centers (P60 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273.
- This funding opportunity was created on 2019-07-11.
- Applicants must submit their applications by 2019-11-14. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,250,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: Comprehensive Alcohol Research Centers (P60 Clinical Trial Optional) (RFA-AA-20-002)
What is the Comprehensive Alcohol Research Centers (P60 Clinical Trial Optional) funding opportunity?
It is a National Institutes of Health (NIH) grant opportunity run through the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The program supports large, interdisciplinary alcohol research centers designed to coordinate multiple investigators and complementary research efforts under a shared scientific vision.
Which NIH institute administers this opportunity?
The opportunity is administered by NIAAA, the National Institute on Alcohol Abuse and Alcoholism, which is part of NIH.
What is the funding opportunity number (RFA)?
The funding opportunity is RFA-AA-20-002.
What does the program aim to fund?
The program aims to fund coordinated, collaborative alcohol research centers that can do more than isolated projects by building shared infrastructure, aligning methods across projects, and advancing alcohol use disorder (AUD) research and broader alcohol-related health impacts.
What is the basic center model NIAAA is looking for?
NIAAA is looking for center-based programs that bring together multiple investigators and complementary lines of work, supported by common resources and cross-cutting methods. The intent is for the center to create a coordinated research program with broader impact than independent, stand-alone projects.
What research topics are within scope?
The scientific scope is intentionally broad. It can include research on the nature and causes of AUD (including etiology and genetics), as well as improvements in diagnosis, treatment, and prevention. It can also include research on alcohol-related end-organ diseases and other health consequences of alcohol.
Does the opportunity focus only on alcohol use disorder (AUD)?
No. While AUD is a central focus, the opportunity also emphasizes alcohol-related end-organ diseases and other health consequences, and it recognizes biomedical, psychosocial, and economic impacts of alcohol across the lifespan.
Are comorbid conditions allowed as part of the research program?
Yes. Where relevant and a significant public health concern, research on comorbid conditions may be included, reflecting that AUD often overlaps with other disorders and health challenges.
Is the scientific scope narrow or broad?
It is broad by design, spanning causes of AUD, genetics and etiology, diagnostic and therapeutic improvement, prevention, and alcohol-related diseases and health consequences across the lifespan.
What is meant by interdisciplinary research centers in this context?
It refers to centers that integrate multiple investigators and complementary lines of work, using shared resources and coordinated methods to address alcohol-related research questions in a unified, collaborative way.
What kinds of expectations does NIAAA have beyond producing research findings?
Beyond findings, centers are expected to provide leadership in alcohol-related research, contribute to development of research methods, and broadly disseminate findings and tools. The center model also emphasizes innovation and durable infrastructure that enables sustained, goal-directed research.
What does innovation and infrastructure mean for this center program?
The opportunity emphasizes building capabilities that support coordinated research, such as shared cores, harmonized protocols, and collaborative structures. These elements are meant to help multiple projects work together efficiently and achieve impact beyond what individual projects could accomplish alone.
Are clinical trials required?
No. Clinical trials are optional. Applicants may propose clinical trials if they fit the aims of the center, but a clinical trial is not required to be competitive.
Can a center include clinical trial work?
Yes. Clinical trials may be proposed if they align with the center's goals and aims, but they are not mandatory.
Who is eligible to apply?
Eligibility is broad and includes many U.S.-based organization types, including various levels of government, higher education institutions (public and private), tribal governments and tribal organizations, public housing authorities, nonprofits (with and without 501(c)(3) status, with certain exclusions as described), for-profit organizations (other than small businesses), and small businesses.
Are state, local, or special district governments eligible?
Yes. Eligible applicants include state, county, city or township, and special district governments.
Are public and private universities eligible?
Yes. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education.
Are independent school districts eligible?
Yes. Independent school districts are listed among eligible applicants.
Are nonprofit organizations eligible?
Yes. Nonprofits with and without 501(c)(3) status are eligible, with the stated exclusion that institutions of higher education are excluded from those nonprofit categories as listed in the opportunity details.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are eligible, and small businesses are also listed as eligible.
Are federally recognized tribal governments eligible?
Yes. Federally recognized Native American tribal governments are included as eligible applicants.
Are tribal organizations eligible even if they are not tribal governments?
Yes. Other Native American tribal organizations are listed as eligible, and tribal governments that are not federally recognized are also explicitly highlighted as eligible applicant types.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are explicitly highlighted among additional eligible applicant types.
Are minority-serving institutions and other specifically named institution types eligible?
Yes. The opportunity explicitly highlights Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and other specified organization categories as eligible applicant types.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly highlighted as eligible applicant types.
Are eligible federal agencies allowed to apply?
Yes. Eligible federal agencies are explicitly highlighted as eligible applicant types.
Can a non-U.S. (foreign) organization apply as the main applicant?
No. Non-domestic (non-U.S.) entities and non-domestic (non-U.S.) institutions are not eligible to apply as the primary applicant organization.
Can a non-U.S. component of a U.S. organization apply?
No. Non-domestic components of U.S. organizations are also not eligible to apply.
Are any foreign collaborations allowed at all?
Yes. Foreign components are allowed when they meet the NIH definition in the NIH Grants Policy Statement. In practical terms, a U.S. applicant may include certain foreign collaborations or activities as part of the overall project when well-justified and consistent with NIH policy.
What type of grant is this?
It is listed as a discretionary grant in the health category.
What is the CFDA number for this program?
The CFDA number provided is 93.273.
What is the award ceiling listed for this opportunity?
The listed award ceiling is $1,250,000.
What was the original closing date shown in the opportunity details?
The original closing date listed is 2019-11-14.
What is the creation date shown in the opportunity details?
The creation date listed is 2019-07-11.
What kinds of impacts does the opportunity recognize from alcohol use?
The opportunity recognizes that alcohol can have biomedical, psychosocial, and economic impacts across the entire lifespan, and it encourages research that addresses these broader consequences where relevant.
What does "center-based" research change compared with separate, individual projects?
The center approach is intended to create a coordinated program where multiple projects and investigators share a scientific vision, common resources, and cross-cutting methods. This structure is meant to enable collaboration, harmonization, and outputs that are larger in impact than the sum of stand-alone efforts.
What does dissemination mean in the context of this funding opportunity?
Dissemination refers to broadly sharing the center's findings, methods, tools, and resources so they can influence the field beyond the funded institution and help advance alcohol-related research more widely.
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