Coordination Center for the Alzheimers Disease Sequencing Project Consortium (U01 Clinical Trial Not Allowed) | RFA AG 25 015

Opportunity Information: Apply for RFA AG 25 015

The National Institutes of Health (NIH), through the National Institute on Aging (NIA), is soliciting applications for a cooperative agreement to run the Coordination Center for the Alzheimer s Disease Sequencing Project (ADSP) consortium under Funding Opportunity Number RFA-AG-25-015. This is a U01 cooperative agreement, meaning the awardee is expected to work closely with NIH staff and other ADSP components in an active, partner-like arrangement rather than operating fully independently. The opportunity is focused on coordination and support of research infrastructure and consortium operations in Alzheimer s disease and Alzheimer s disease-related dementias (AD/ADRD) genetics and genomics. Clinical trials are not allowed under this announcement.

The core purpose of the Coordination Center is to provide leadership and technical expertise across essentially all operational aspects of ADSP research. In practical terms, the Center is meant to be the organizing hub that makes a large, multi-site, multi-component sequencing and genomics consortium function smoothly. The Center is expected to lead and coordinate cross-consortium activities such as establishing and maintaining effective communication channels, enabling collaboration among participating groups, organizing outreach to key stakeholders, supporting dissemination of consortium outputs, providing training resources or events, and ensuring coordination across the different ADSP components. A major emphasis is that the Coordination Center serves as the main conduit for collaboration between ADSP and other NIH and NIA-funded programs, while also connecting ADSP with the broader global research community working in AD/ADRD genetics and genomics. In other words, the award is geared toward making ADSP more integrated, visible, and interoperable with related efforts so that data, methods, standards, and findings can move efficiently across programs and into wider use.

The applicant pool is intentionally broad and includes many types of U.S.-based organizations that can credibly manage complex consortium coordination. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding higher education institutions when specified); for-profit organizations (other than small businesses); and small businesses. The announcement also highlights additional eligible categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. At the same time, it clearly excludes non-domestic (non-U.S.) entities from applying, does not allow non-domestic components of U.S. organizations to apply, and prohibits foreign components as defined by the NIH Grants Policy Statement. The net effect is that the coordinating entity and all participating components supported under this award must be fully domestic.

Key administrative details provided in the listing include an original application due date of 2025-02-14 and an award ceiling of $1,000,000. The opportunity is categorized as discretionary funding, within the health funding activity category, and is associated with CFDA number 93.866. While the expected number of awards is not specified in the provided text, the structure and purpose suggest NIH is looking for a single, central Coordination Center capable of serving the whole consortium and acting as the primary operational and collaborative interface for ADSP.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Coordination Center for the Alzheimers Disease Sequencing Project Consortium (U01 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
• This funding opportunity was created on 2024-12-09.
• Applicants must submit their applications by 2025-02-14. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA AG 25 015

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