Opportunity Information: Apply for RFA AT 24 011
This funding opportunity (RFA-AT-24-011) from the National Institutes of Health supports new Demonstration Projects within the NIH-DoD-VA Pain Management Collaboratory (PMC) under the HEAL Initiative. The core aim is to fund efficient, large-scale pragmatic clinical trials and/or implementation science projects that test non-opioid approaches to pain management for U.S. veterans, active-duty military personnel, and their families, including attention to pain-related comorbid conditions. The work is intended to produce practical, real-world evidence that can be adopted in the health systems that serve these populations, rather than remaining confined to highly controlled research environments.
The award uses a UG3/UH3 phased cooperative agreement structure and requires a clinical trial. In practice, this means applicants propose a two-stage project where the initial UG3 phase is typically used to finalize key start-up activities (for example, confirming feasibility, refining protocols, establishing site readiness, and meeting defined milestones), and the UH3 phase supports full implementation and execution of the pragmatic trial and/or implementation study once those milestones are met. Because this is a cooperative agreement, NIH involvement is more hands-on than in a standard grant mechanism, with NIH program staff expected to have substantial scientific and programmatic involvement during the project.
A defining feature of the opportunity is that projects must be conducted within the existing PMC infrastructure. The PMC includes a Coordinating Center established in 2017 that provides national leadership and technical expertise across PMC studies. Awardees can expect coordinated support related to pragmatic trial methods, implementation science approaches, data and informatics considerations, regulatory and operational alignment across sites, and other common challenges that arise when conducting large-scale studies in military and veteran health care contexts. The overall intent is to accelerate high-quality, scalable research by leveraging this shared infrastructure instead of building trial operations from scratch.
The topic focus is squarely on non-opioid pain management solutions, aligning with the HEAL Initiative, an NIH-wide effort to address the opioid crisis partly by identifying and validating effective pain treatments that reduce reliance on opioids. In addition, the National Center for Complementary and Integrative Health (NCCIH) is highlighting a whole person approach to pain management as a priority emphasis, meaning applicants are encouraged to consider pain in the broader context of physical, behavioral, and social factors and how integrated care strategies may improve outcomes. Partnering NIH Institutes, Centers, and Offices may also bring additional priority areas as long as they include pain as a component, so projects that thoughtfully connect pain management with relevant comorbidities may be particularly responsive.
Eligibility is broad across public, nonprofit, and private sectors. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public housing authorities/Indian housing authorities; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and federally recognized Native American tribal governments and certain tribal organizations. The announcement also explicitly calls out additional eligible groups such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible agencies of the federal government.
Foreign participation is constrained. Non-domestic (non-U.S.) entities are not eligible to apply, and non-domestic components of U.S. organizations are not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed, which generally means a U.S.-based applicant may include certain foreign elements when clearly justified and allowable under NIH policy.
Administratively, the opportunity is categorized as a discretionary program and uses the cooperative agreement funding instrument type in the health activity category, with CFDA numbers 93.213, 93.273, and 93.866. The original application closing date listed is 2024-11-07, and the notice was created on 2024-08-09. Award ceiling and expected number of awards are not specified in the provided listing, so applicants would need to consult the full NOFO for budget limits, project period expectations, and any caps or set-asides.
Overall, the opportunity is designed for teams that can run a required clinical trial in real-world military and veteran care settings, using pragmatic and/or implementation science methods, and that can work within the PMC framework to generate results that are credible, operationally relevant, and ready for adoption as non-opioid pain management solutions.Apply for RFA AT 24 011
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "HEAL Initiative: NIH-DOD-VA Pain Management Collaboratory Pragmatic and/or Implementation Science Demonstration Projects ((UG3/UH3) Clinical Trial Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213, 93.273, 93.866.
- This funding opportunity was created on 2024-08-09.
- Applicants must submit their applications by 2024-11-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Browse more opportunities from the same category: Health
Next opportunity: Self-Help Homeownership Opportunity Program (SHOP)
Previous opportunity: American Spaces Programing Grant
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA AT 24 011
Applicants also applied for:
Applicants who have applied for this opportunity (RFA AT 24 011) also looked into and applied for these:
| Funding Opportunity |
|---|
| Research Grants to Rigorously Evaluate Innovative and Promising Strategies to Prevent Firearm-Related Violence and Injuries Apply for RFA CE 25 030 Funding Number: RFA CE 25 030 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $650,000 |
| Rigorous Evaluation of Community- and Societal-Level Primary Prevention Approaches to Prevent Adverse Childhood Experiences (ACEs): Expanding the Best Available Evidence Apply for RFA CE 25 025 Funding Number: RFA CE 25 025 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $450,000 |
| Grants to Support New Investigators in Conducting Research Related to Preventing Interpersonal Violence Impacting Children and Youth Apply for RFA CE 25 029 Funding Number: RFA CE 25 029 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $150,000 |
| Effectiveness Research to Prevent Polysubstance-Impaired Driving Apply for RFA CE 25 028 Funding Number: RFA CE 25 028 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $350,000 |
| Rigorous Evaluation of Primary and Secondary Overdose Prevention Activities Among Populations Disproportionately Affected by Overdose Apply for RFA CE 25 149 Funding Number: RFA CE 25 149 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $700,000 |
| Environmental Health Specialists Network (EHS-Net) Practice-based Research to Improve Food Safety Apply for RFA EH 25 011 Funding Number: RFA EH 25 011 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $200,000 |
| Rigorously Evaluating Programs and Policies to Prevent Child Sexual Abuse and Problematic Sexual Behavior among Youth Apply for RFA CE 25 026 Funding Number: RFA CE 25 026 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $400,000 |
| Research Grants for Preventing Violence and Violence Related Injury (R01) Apply for RFA CE 25 021 Funding Number: RFA CE 25 021 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $400,000 |
| Evaluate STEADI-based Fall Prevention in Assisted Living Facilities Apply for RFA CE 25 027 Funding Number: RFA CE 25 027 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $700,000 |
| Formative Research of Community-led Primary Prevention Approaches to Address Elevated Risk of Intimate Partner Violence & Sexual Violence Apply for RFA CE 25 032 Funding Number: RFA CE 25 032 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $375,000 |
| Rigorously Evaluating Primary Prevention Strategies for Intimate Partner Violence and Sexual Violence Apply for RFA CE 25 031 Funding Number: RFA CE 25 031 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $500,000 |
| AIDS Drug Assistance Program (ADAP) Emergency Relief Funds (ERF) Apply for HRSA 25 046 Funding Number: HRSA 25 046 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Ending the HIV Epidemic in the U.S. – Ryan White HIV/AIDS Program Parts A and B Apply for HRSA 25 063 Funding Number: HRSA 25 063 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Ending the HIV Epidemic in the U.S. – Systems Coordination Provider Apply for HRSA 25 065 Funding Number: HRSA 25 065 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Ending the HIV Epidemic in the U.S. – Technical Assistance Provider Apply for HRSA 25 064 Funding Number: HRSA 25 064 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Service Area Competition Apply for HRSA 25 017 Funding Number: HRSA 25 017 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Service Area Competition Apply for HRSA 25 016 Funding Number: HRSA 25 016 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Cell and Gene Therapy (CGT) Access Model Apply for CMS 2P2 25 001 Funding Number: CMS 2P2 25 001 Agency: Centers for Medicare Medicaid Services Category: Health Funding Amount: $9,550,000 |
| USAID/Ethiopia Health Financing Activity Apply for 72066324RFA00012 Funding Number: 72066324RFA00012 Agency: Ethiopia USAID-Addis Ababa Category: Health Funding Amount: $40,000,000 |
| Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) (R24 - Clinical Trial Not Allowed) Apply for PAR 24 260 Funding Number: PAR 24 260 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA AT 24 011", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.