Opportunity Information: Apply for CDC RFA GH22 2234
This funding opportunity, titled "Delivering Comprehensive and Sustainable HIV/AIDS Clinical and Community Services to Achieve HIV Epidemic Control in Subnational Units in Nigeria under PEPFAR" (Funding Opportunity Number CDC RFA GH22 2234), is a CDC cooperative agreement designed to support Nigeria in reaching and sustaining HIV epidemic control. It sits within the PEPFAR framework and focuses on strengthening high-quality HIV care and treatment services at both facility and community levels across multiple Nigerian states, with an explicit emphasis on performance, equity, and long-term sustainability in partnership with the Government of Nigeria (GON).
The funding structure is a bit unusual on paper: the Year 1 award ceiling is listed as 0 (meaning CDC is not setting a maximum cap per award in that field), but CDC anticipates about 160,000,000 USD in total FY funding for Year 1 across all awards, subject to funds being available. Rather than applying for the entire 160,000,000 USD, applicants are instructed to apply to the approximate average one-year award amount of 40,000,000 USD. Applicants are expected to build a workplan and budget that spends roughly 40,000,000 USD to implement activities in 4 to 5 states, and those states must include at least one high-burden state. CDC anticipates making about 4 awards, and the final funding level and the exact geographic scope for each recipient will be set at the time of award based on programmatic decisions and available funds.
Programmatically, the goal is to help the GON achieve HIV epidemic control across CDC-supported states, with results monitored within age and sex bands to ensure progress is not masking gaps for specific groups (for example, adolescents, men, or other populations that may have lower testing or treatment coverage). Implementing partners are expected to deliver comprehensive HIV care and treatment services that push toward the UNAIDS 95-95-95 targets by 2030: 95 percent of people living with HIV knowing their status, 95 percent of those diagnosed receiving sustained antiretroviral therapy (ART), and 95 percent of those on ART achieving viral suppression. The opportunity recognizes Nigeria has made important gains, but argues that epidemic control will require continued, accelerated ART scale-up paired with proven prevention, treatment, and retention approaches to reduce new infections and HIV-related deaths.
A central theme is client-centered service delivery using differentiated service delivery (DSD) models. In practice, this typically means tailoring how care is delivered to different patient needs and contexts rather than using a single uniform clinic model for everyone. The NOFO highlights the use of evidence-based, client-centered models supported by real-time data collection, analysis, and continuous quality improvement (QI). The intent is to improve program performance and accountability, identify problems quickly (like treatment interruptions, low viral load coverage, or poor retention in certain sites or populations), and rapidly implement fixes using data-driven management approaches.
Another key feature is integration. The NOFO explicitly promotes integrating HIV service delivery with the management of other infectious and non-communicable diseases, calling out tuberculosis (TB) and COVID-19 in particular. This reflects the reality that people living with HIV often need services that intersect with TB screening and treatment, respiratory infection management, and broader chronic care systems. Integration is also positioned as a way to make programs more resilient and efficient, reduce fragmentation for patients, and strengthen health systems rather than building isolated HIV-only service lanes.
The opportunity also emphasizes prioritizing at-risk and marginalized populations through targeted, client-centered interventions. While the summary text does not list specific population categories, the direction is clear: partners should design approaches that actively reach people who are frequently missed by standard facility-based services, address barriers such as stigma or access limitations, and ensure that the scale-up of testing, treatment initiation, and retention does not leave behind groups with historically lower coverage and worse outcomes.
Finally, sustainability is not treated as an add-on but as a required direction of travel. Recipients are expected to jointly develop a phased sustainability framework with the GON to guide implementation across all sub-national units (SNUs). The idea is to move beyond short-term service delivery outputs and strengthen local ownership, local partnerships, and the operational commitments needed to maintain epidemic control over time. In a cooperative agreement context, this also implies substantial CDC involvement in strategic direction and collaboration, with recipients working closely with CDC and national and subnational stakeholders to align with Nigeria's HIV response architecture.
Administrative details from the source data include that this is a discretionary funding opportunity under CFDA 93.067, issued by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), Center for Global Health (CGH). Eligibility is listed as unrestricted (open broadly to entity types, subject to any specific clarifications in the full notice). The opportunity was created December 28, 2021, with an original application closing date of February 28, 2022, and electronically submitted applications due by 11:59 pm Eastern Time on the deadline date.Apply for CDC RFA GH22 2234
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Delivering Comprehensive and Sustainable HIV/AIDS Clinical and Community Services to Achieve HIV Epidemic Control in Subnational Units in Nigeria under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Dec 28, 2021.
- Applicants must submit their applications by Feb 28, 2022 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs)
1) What is the title and funding opportunity number for this grant?
The opportunity is titled "Delivering Comprehensive and Sustainable HIV/AIDS Clinical and Community Services to Achieve HIV Epidemic Control in Subnational Units in Nigeria under PEPFAR." The Funding Opportunity Number is CDC RFA GH22 2234.
2) What type of award is this?
This is a CDC cooperative agreement. In a cooperative agreement, CDC typically has substantial involvement in the program’s strategic direction and collaboration during implementation, rather than acting only as a pass-through funder.
3) Which agency is offering this opportunity?
The opportunity is issued by the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), Center for Global Health (CGH).
4) What is the CFDA number associated with this funding?
The CFDA number listed is 93.067.
5) What is the overall purpose of the opportunity?
The purpose is to support Nigeria in reaching and sustaining HIV epidemic control under PEPFAR by strengthening high-quality HIV care and treatment services at both facility and community levels, with a strong focus on performance, equity, and long-term sustainability in partnership with the Government of Nigeria (GON).
6) Where will the work take place?
The work is intended to be implemented in multiple Nigerian states across CDC-supported subnational units (SNUs). Applicants are expected to implement activities in 4 to 5 states.
7) Do the selected states have to meet any specific requirement?
Yes. The 4 to 5 states included in an application must include at least one high-burden state.
8) How many awards does CDC expect to make?
CDC anticipates making about 4 awards.
9) How much funding is available for Year 1?
CDC anticipates approximately 160,000,000 USD in total FY funding for Year 1 across all awards, subject to the availability of funds.
10) Why does the Year 1 award ceiling show as 0?
The Year 1 award ceiling is listed as 0, which indicates CDC is not setting a maximum cap per award in that specific field. However, CDC still provides funding expectations and budgeting guidance elsewhere in the opportunity description.
11) How much should an applicant request in its budget?
Applicants are instructed to apply to the approximate average one-year award amount of 40,000,000 USD and to build a workplan and budget that spends roughly 40,000,000 USD to implement activities in 4 to 5 states (including at least one high-burden state).
12) Should applicants apply for the full 160,000,000 USD?
No. The guidance indicates applicants should not apply for the entire anticipated total Year 1 amount. Instead, applicants should budget around the approximate average one-year award amount of 40,000,000 USD.
13) Will the final award amount and geographic scope match exactly what the applicant proposes?
Not necessarily. The final funding level and the exact geographic scope for each recipient will be set at the time of award based on programmatic decisions and available funds.
14) What major program results is this opportunity aiming to achieve?
The program aims to help the Government of Nigeria achieve HIV epidemic control across CDC-supported states, with results monitored within age and sex bands to ensure progress is not hiding gaps among specific groups.
15) What global targets does the program reference?
The opportunity explicitly references the UNAIDS 95-95-95 targets by 2030: 95 percent of people living with HIV knowing their status, 95 percent of those diagnosed receiving sustained antiretroviral therapy (ART), and 95 percent of those on ART achieving viral suppression.
16) What kinds of services are expected under this award?
Implementing partners are expected to deliver comprehensive HIV care and treatment services at both facility and community levels. The program emphasis is on accelerating ART scale-up and using proven prevention, treatment, and retention approaches to reduce new infections and HIV-related deaths.
17) How will performance be monitored to ensure equity?
The opportunity notes that results will be monitored within age and sex bands so that overall progress does not mask gaps for specific groups (for example, adolescents, men, or other populations with lower testing or treatment coverage).
18) What is meant by client-centered service delivery in this opportunity?
The opportunity emphasizes client-centered service delivery using differentiated service delivery (DSD) models, meaning care delivery should be tailored to different patient needs and contexts rather than using one uniform clinic model for everyone.
19) What role does data play in the program approach?
Evidence-based, client-centered models are expected to be supported by real-time data collection and analysis, along with continuous quality improvement (QI). The intent is to quickly identify issues (like treatment interruptions, low viral load coverage, or poor retention) and implement fixes using data-driven management approaches.
20) Does the opportunity emphasize integration with other health services?
Yes. The opportunity promotes integrating HIV service delivery with the management of other infectious and non-communicable diseases, specifically calling out tuberculosis (TB) and COVID-19. Integration is positioned as a way to improve resilience and efficiency, reduce fragmentation for patients, and strengthen broader health systems.
21) Are community-based activities included, or is it only facility-based work?
The opportunity is explicitly focused on both clinical (facility) and community services, aiming to strengthen care and treatment services across both settings.
22) Does the opportunity address at-risk or marginalized populations?
Yes. The opportunity emphasizes prioritizing at-risk and marginalized populations through targeted, client-centered interventions, with an expectation that partners address barriers such as stigma or access limitations and reach people who are often missed by standard facility-based services.
23) What is the expectation around sustainability?
Sustainability is treated as a core requirement. Recipients are expected to jointly develop a phased sustainability framework with the Government of Nigeria to guide implementation across all sub-national units, strengthening local ownership and the commitments needed to maintain epidemic control over time.
24) How does the cooperative agreement structure relate to working with CDC and the Government of Nigeria?
The opportunity indicates close collaboration among recipients, CDC, and national and subnational stakeholders, with alignment to Nigeria’s HIV response architecture and joint work on strategic direction and sustainability planning.
25) Who is eligible to apply?
Eligibility is listed as unrestricted, meaning it is broadly open to entity types, subject to any additional clarifications that may appear in the full notice.
26) When was this opportunity created?
The opportunity was created on December 28, 2021.
27) What was the application deadline for the original posting?
The original application closing date was February 28, 2022.
28) How were applications required to be submitted, and what time were they due?
Applications were to be submitted electronically, and they were due by 11:59 pm Eastern Time on the deadline date.
29) Is this opportunity connected to PEPFAR?
Yes. The opportunity sits within the PEPFAR framework and is designed to support Nigeria in achieving and sustaining HIV epidemic control.
30) What is the intended scale of implementation per award?
Each applicant is expected to propose a workplan and budget at roughly 40,000,000 USD for one year to implement activities across 4 to 5 Nigerian states, including at least one high-burden state. CDC then determines the final scope and funding at award based on programmatic decisions and funds availability.
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